Waters Chromatography System | ACQUITY ...
With the ACQUITY UPC2 System, the orthogonal capability of normal-phase LC has been elevated to a mainstream technique: Convergence Chromatography.
Bringing ease-of-use to normal-phase LC
By providing the ability to precisely vary mobile phase strength, pressure, and temperature, the Waters ACQUITY UPC2 System gives scientists the power to better control the retention of analytes for separating, detecting, and quantifying structural analogs, isomers, and enantiomeric and diasteriomeric mixtures.
Unparalleled resolving power and selectivity
With its separation potential for a far broader chemical spectrum of applications than that of reversed-phase LC-based instrumentation, the ACQUITY UPC2 System leverages convergence chromatography to enable superior performance, using inexpensive, compressed CO2 as a non-toxic mobile phase.
Retention mechanisms and orthogonality to RPLC
Harnessing what's now known as convergence chromatography, an evolution of the traditional SFC technique, the ACQUITY UPC2 System has the power to create selective separations of structurally similar chiral and achiral compounds.
The miscibility of CO2 with a wide range of polar and non-polar organic solvents has made the liquid CO2-based mobile phase versatile enough to separate a much wider range of compounds than reversed-phase LC, especially for mixtures containing polar compounds. Not only can CO2-based solvents be used with both polar and non-polar stationary phases, but chromatography can be influenced by modulating solvent gradients with a much wider choice of columns using the same mass spectrometry-compatible co-solvents.
Being orthogonal to reversed-phase LC, UPC2 separations often show an inverse order of elution among groups of analytes. In combination with various detection techniques, this orthogonality is valuable for confirming analyte identity in complex matrices.
To contact Waters Australia about Waters Chromatography System | ACQUITY UPC2 System use Get a quote.
With the ACQUITY UPC2 System, the orthogonal capability of normal-phase LC has been elevated to a mainstream technique: Convergence Chromatography.
Bringing ease-of-use to normal-phase LC
By providing the ability to precisely vary mobile phase strength, pressure, and temperature, the Waters ACQUITY UPC2 System gives scientists the power to better control the retention of analytes for separating, detecting, and quantifying structural analogs, isomers, and enantiomeric and diasteriomeric mixtures.
Unparalleled resolving power and selectivity
With its separation potential for a far broader chemical spectrum of applications than that of reversed-phase LC-based instrumentation, the ACQUITY UPC2 System leverages convergence chromatography to enable superior performance, using inexpensive, compressed CO2 as a non-toxic mobile phase.
Retention mechanisms and orthogonality to RPLC
Harnessing what's now known as convergence chromatography, an evolution of the traditional SFC technique, the ACQUITY UPC2 System has the power to create selective separations of structurally similar chiral and achiral compounds.
The miscibility of CO2 with a wide range of polar and non-polar organic solvents has made the liquid CO2-based mobile phase versatile enough to separate a much wider range of compounds than reversed-phase LC, especially for mixtures containing polar compounds. Not only can CO2-based solvents be used with both polar and non-polar stationary phases, but chromatography can be influenced by modulating solvent gradients with a much wider choice of columns using the same mass spectrometry-compatible co-solvents.
Being orthogonal to reversed-phase LC, UPC2 separations often show an inverse order of elution among groups of analytes. In combination with various detection techniques, this orthogonality is valuable for confirming analyte identity in complex matrices.
To contact Waters Australia about Waters Chromatography System | ACQUITY UPC2 System use Get a quote.
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