Tewitro TW 24 | Skin Analyser for sale from Medisa

Tewitro TW 24 | Skin Analyser

Supplier: Medisa

Tewitro TW 24 | Skin Analyser

Tewitro TW 24 Transepidermal Waterloss Measurement in Skin Tissue Models

In Stock

The Tewitro® TW 24 is the only device to measure the water evaporation from cultured tissue sets (wells in a plate with medium) in up to 24 wells simultaneously with the worldwide most used “open chamber” measurement of the Tewameter®.

Fields of Application

For each product to be applied to the skin, safetymeasurements are indispensable. The use of skin tissue models for long-term safety tests is a quick and easy method to avoid using animals or volunteers.

It is the only way to study skin permeability and dermal absorption necessary for safety and efficacy testing
In vitro tests and procedures to minimize the use of animals in tests are established in several worldwide acknowledged guidelines: e.g. ECVAM (European Centre for the Validation of Alternatives to Animal Testing), OECD (Organisation for Economic Co-operation and Development) or REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals)

Whenever the barrier is damaged, the evaporation rate will increase immediately. Also for claims related to barrier improvement/enhancing, tests on cultured cells are needed, as products meant to keep the barrier intact or to even improve it, can be detected by a stable Transepidermal Water Loss (TEWL).

The Tewitro® is well-suited to non-invasively monitor TEWL of cultured skin tissue samples. These results open up new opportunities to monitor the dermal barrier physiology under different experimental conditions and treatments in vitro.

Software

The convenient and organized software offers 24 TEWL-values (one for each measurement inlet), with two different adjustable averages and their respective standard deviations as well as the possibility of displaying and saving the RH and temperature value for the upper and lower sensor pair for each measurement inlet (2 x 24) separately.
Graphical view for each measurement inlet with one click
Measurements from a couple of seconds up to 24 h long-term studies are possible.
Automatic stop conditions for the measurement (stability of the measurement or time)
Warning displayed, if RH exceeds the range for regular measurement uncertainty.
Easy & quick check calibration and offset
If the Ambient Condition Sensor probe is connected, its values are constantly recorded during the measurement and saved with the results.

Fields of Application

It is the only way to study skin permeability and dermal absorption necessary for safety and efficacy testing
In vitro tests and procedures to minimize the use of animals in tests are established in several worldwide acknowledged guidelines: e.g. ECVAM (European Centre for the Validation of Alternatives to Animal Testing), OECD (Organisation for Economic Co-operation and Development) or REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals)

Software

The convenient and organized software offers 24 TEWL-values (one for each measurement inlet), with two different adjustable averages and their respective standard deviations as well as the possibility of displaying and saving the RH and temperature value for the upper and lower sensor pair for each measurement inlet (2 x 24) separately.
Graphical view for each measurement inlet with one click
Measurements from a couple of seconds up to 24 h long-term studies are possible.
Automatic stop conditions for the measurement (stability of the measurement or time)
Warning displayed, if RH exceeds the range for regular measurement uncertainty.
Easy & quick check calibration and offset
If the Ambient Condition Sensor probe is connected, its values are constantly recorded during the measurement and saved with the results.

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